A post in a forum says that the size of a homepage doesn’t matter in SEO but it will matter to users when they open the site it will take lots of time and that won’t do any good – that could be irritating at times. And also having too many links on home and as many as 1000 is really not good in an SEO point of view as you are transferring all your link juice to other sites and pages.
http://forums.digitalpoint.com/showthread.php?t=1474229